Effects of salbutamol on airway characteristics in mechanically ventilated adults without COPD

effects of thoracic squeezing on airway secretion removal in mechanically ventilated patients

abstract background: accumulation of secretions in the airways of patients with an endotracheal tube and mechanical ventilation will have serious consequences. one of the most common methods of airway clearance is endotracheal suctioning. in order to facilitate discharge of airway secretion resulting in promotion of gas exchange, chest physiotherapy techniques can be used at the time of expirat...

Effects of PEEP on inspiratory resistance in mechanically ventilated COPD patients.

This study aimed to investigate the effect of increased lung volume with positive end-expiratory pressure (PEEP) on respiratory resistance in patients with chronic obstructive pulmonary disease (COPD). Ten patients with COPD were mechanically ventilated for acute respiratory failure. PEEP was set at 0, 5, 10 and 15 cm H2O. Using the rapid airway occlusion technique, the total inspiratory resist...

Effects of formoterol, salmeterol or oxitropium bromide on airway responses to salbutamol in COPD.

We examined whether a pretreatment with formoterol, oxitropium bromide, or salmeterol might modify the dose-response curves to inhaled salbutamol in patients with stable and partially reversible chronic obstructive pulmonary disease (COPD). Sixteen outpatients with partially reversible, stable COPD received 24 microg formoterol, 50 microg salmeterol, 200 microg oxitropium bromide, or placebo on...

Airway colonization, pathogenesis and prognosis in mechanically ventilated patients

A Patient-Specific Airway Branching Model for Mechanically Ventilated Patients

BACKGROUND Respiratory mechanics models have the potential to guide mechanical ventilation. Airway branching models (ABMs) were developed from classical fluid mechanics models but do not provide accurate models of in vivo behaviour. Hence, the ABM was improved to include patient-specific parameters and better model observed behaviour (ABMps). METHODS The airway pressure drop of the ABMps was ...